What is Extra Super Tadarise?
Extra Super Tadarise is a dual-action prescription tablet that treats two of the most common male sexual health conditions simultaneously: Erectile Dysfunction (ED) and Premature Ejaculation (PE). Each tablet contains Tadalafil 40mg, a long-acting PDE5 inhibitor that improves penile blood flow for firm, sustained erections, and Dapoxetine 60mg, a fast-acting SSRI that delays the ejaculatory reflex and extends time to ejaculation.
Unlike taking two separate medications, Extra Super Tadarise delivers a synergistic effect in a single tablet, making it a practical, cost-effective option for men experiencing both ED and PE together.
Quick Facts
| Brand Name | Extra Super Tadarise |
| Generic Name | Tadalafil 40mg + Dapoxetine 60mg |
| Manufacturer | Sunrise Remedies Pvt. Ltd., India (WHO-GMP Certified) |
| Drug Class | PDE5 Inhibitor + SSRI (Short-acting) |
| Indications | Erectile Dysfunction (ED) + Premature Ejaculation (PE) |
| Onset | 30–60 minutes after oral administration |
| Duration | Tadalafil: up to 36 hours | Dapoxetine: 1–3 hours |
| Pack Sizes | 30 / 60 / 90 Tablets (Blister Pack) |
| Prescription | Required (Rx Only) |
| Supplier | Titan Exim – WHO-GMP Certified Generics |
Active Ingredients & Mechanism of Action
1. Tadalafil USP 40mg – PDE5 Inhibitor
Tadalafil is the active ingredient in brand-name Cialis. It works by selectively inhibiting the phosphodiesterase type-5 (PDE5) enzyme in the smooth muscle of the corpora cavernosa. Sexual stimulation triggers the release of nitric oxide (NO), which produces cyclic guanosine monophosphate (cGMP). cGMP relaxes smooth muscle and dilates blood vessels in the penis, allowing increased blood inflow and a firm erection. Tadalafil prevents cGMP from breaking down, prolonging and strengthening this effect.
Key advantage: Tadalafil has the longest duration of action among PDE5 inhibitors — up to 36 hours — allowing for greater spontaneity compared to sildenafil (4–6 hours).
2. Dapoxetine HCl 60mg – Short-Acting SSRI
Dapoxetine is the world’s first oral medication specifically designed for premature ejaculation. Unlike standard antidepressant SSRIs taken daily, dapoxetine is formulated for on-demand use due to its rapid absorption (Tmax: ~1.2 hours) and short half-life (~1.5 hours). It inhibits the presynaptic serotonin transporter (SERT), increasing serotonin activity at the synaptic cleft. This modulates the ejaculatory threshold, significantly delaying the ejaculatory reflex and increasing intravaginal ejaculatory latency time (IELT).
Indications & Uses
Extra Super Tadarise is prescribed for adult men who experience both conditions concurrently:
- Erectile Dysfunction (ED): Difficulty achieving or maintaining an erection sufficient for satisfactory sexual activity.
- Premature Ejaculation (PE): Persistent or recurrent ejaculation with minimal sexual stimulation before or shortly after penetration, causing distress.
| Clinical Note: Studies show 30–40% of men with ED also experience PE. Using a combination therapy addresses both simultaneously, improving overall sexual satisfaction and quality of life. |
Dosage & Administration
Recommended Dose
- Standard dose: 1 tablet (Tadalafil 40mg + Dapoxetine 60mg) orally with water
- Take 30–60 minutes before anticipated sexual activity
- Do NOT exceed 1 tablet in any 24-hour period
- For as-needed use only — not intended for daily chronic therapy
How to Take
- Swallow tablet whole with a glass of water
- Can be taken with or without food (light meals preferred; heavy/fatty meals may slow dapoxetine absorption)
- Avoid alcohol before or during use — increases hypotension and dizziness risk
- Avoid grapefruit juice for at least 24 hours — inhibits CYP3A4 and raises plasma drug levels
Onset & Duration
| Component | Onset | Peak Effect | Duration |
| Tadalafil 40mg | 30–60 min | ~2 hours | Up to 36 hours |
| Dapoxetine 60mg | ~1 hour | ~1.2 hours | 1–3 hours |
Contraindications – Who Should NOT Take This Medication
| Do NOT take Extra Super Tadarise if any of the following apply. Failure to observe contraindications can result in life-threatening medical emergencies. |
- Nitrate therapy (ABSOLUTE CONTRAINDICATION): Patients taking any form of organic nitrate (nitroglycerin, isosorbide mono/dinitrate, amyl nitrate/poppers) — combination causes severe, potentially fatal hypotension.
- Recent cardiovascular events: Heart attack, stroke, or unstable angina within the past 6 months.
- Severe hypotension: Resting BP < 90/50 mmHg or uncontrolled hypertension.
- Severe hepatic impairment: Child-Pugh Class C liver disease — both drugs are hepatically metabolized.
- Concurrent SSRI/SNRI/MAOI therapy: Dapoxetine combined with other serotonergic agents raises serotonin syndrome risk.
- Other PDE5 inhibitors: Sildenafil, vardenafil, avanafil — additive hypotension.
- Known hypersensitivity: To tadalafil, dapoxetine, or any excipient.
- Hereditary retinitis pigmentosa: Rare genetic eye condition with increased risk of visual side effects.
- Age < 18 years: Not indicated; safety and efficacy not established.
- Women: Not indicated for female use.
Side Effects
Common Side Effects (Usually Mild and Transient)
These effects typically resolve as the body adjusts to the medication:
| From Tadalafil | From Dapoxetine |
| Headache, facial flushing | Nausea, dry mouth |
| Indigestion / dyspepsia | Dizziness, drowsiness |
| Nasal congestion | Diarrhea |
| Back pain, muscle aches | Increased sweating |
| Blurred vision | Fatigue / weakness |
| Hypotension (blood pressure drop) | Insomnia |
Serious Side Effects – Seek Immediate Medical Attention
| Stop taking this medication immediately and call emergency services if you experience any of the following: |
- Priapism: Erection lasting longer than 4 hours (medical emergency — can cause permanent erectile damage)
- Sudden vision loss (NAION — Non-Arteritic Anterior Ischemic Optic Neuropathy) or significant visual changes
- Sudden decrease or complete loss of hearing, with or without tinnitus
- Chest pain, irregular heartbeat, palpitations, or signs of heart attack
- Syncope (fainting) or severe dizziness
- Serotonin Syndrome: Agitation, rapid heart rate, fever, sweating, tremor, muscle rigidity (from dapoxetine interactions)
- Severe allergic reaction: Rash, hives, swelling of face/lips/tongue/throat, difficulty breathing
Drug Interactions
| Drug/Substance | Severity | Interaction |
| Organic nitrates (nitroglycerin, isosorbide) | CONTRAINDICATED | Severe hypotension, potentially fatal |
| Other PDE5 inhibitors (sildenafil, vardenafil) | CONTRAINDICATED | Additive hypotension |
| MAOIs (phenelzine, tranylcypromine) | CONTRAINDICATED | Serotonin syndrome risk |
| SSRIs / SNRIs (fluoxetine, sertraline, venlafaxine) | AVOID | Serotonin syndrome; also raises dapoxetine levels |
| Alpha-blockers (doxazosin, tamsulosin) | CAUTION | Additive blood pressure drop; use lowest dose |
| CYP3A4 inhibitors (ketoconazole, ritonavir, clarithromycin) | CAUTION | Increases tadalafil and dapoxetine plasma levels |
| CYP3A4 inducers (rifampin, St. John’s Wort) | CAUTION | Reduces efficacy of both active ingredients |
| Alcohol | AVOID | Potentiates hypotension, dizziness, syncope |
| Grapefruit juice | AVOID | CYP3A4 inhibition raises plasma drug levels |
| Tramadol | AVOID | Increased serotonin syndrome risk with dapoxetine |
| Always disclose ALL medications, supplements, and herbal products to your prescribing physician before starting Extra Super Tadarise. |
Warnings & Special Precautions
- Cardiovascular risk: Sexual activity increases cardiac demand. Men with underlying heart disease, recent MI/stroke, or arrhythmias require thorough cardiac evaluation before use.
- Driving and machinery: Dapoxetine may cause dizziness, drowsiness, or syncope. Avoid driving immediately after dosing until your individual response is known.
- Orthostatic hypotension: Risk is highest when standing up quickly. Rise slowly from sitting/lying positions.
- Priapism risk groups: Men with sickle cell anemia, multiple myeloma, leukemia, or Peyronie’s disease are at elevated risk.
- Hepatic impairment: Moderate impairment (Child-Pugh B): use with caution and dose adjustment. Severe impairment: contraindicated.
- Renal impairment: GFR < 30 mL/min — avoid use; dose adjustment required for moderate impairment.
- Syncope with dapoxetine: Stand or sit for a few minutes after taking the tablet before resuming normal activity.
- Long-term use: Safety beyond 24 weeks of continuous use has not been fully established. Regular follow-up every 6 months is recommended.
Storage Instructions
- Store at room temperature: 20–25°C (68–77°F)
- Keep in original blister packaging; protect from moisture and direct sunlight
- Do not store in bathroom medicine cabinets (heat + humidity)
- Keep out of reach of children and pets
- Do not use after the expiry date printed on the packaging
Packaging & Pack Sizes
| Pack Size | Unit Price (est.) | Best For | Savings |
| 30 Tablets | $1.60/tab | First-time buyers | — |
| 60 Tablets | $1.42/tab | Regular users | ~11% vs 30-pack |
| 90 Tablets | $1.28/tab | Bulk / wholesale | ~20% vs 30-pack |
Each pack contains blister strips of 10 tablets. Cartons are clearly labeled with drug name, active ingredients, strengths, batch number, and expiry date per WHO-GMP standards.
Frequently Asked Questions (FAQ)
Q1: What is Extra Super Tadarise used for?
Extra Super Tadarise is used to treat both erectile dysfunction (ED) and premature ejaculation (PE) simultaneously in adult men. Tadalafil helps achieve and maintain a firm erection, while dapoxetine delays ejaculation for improved sexual performance and satisfaction.
Q2: How and when should I take Extra Super Tadarise?
Take 1 tablet orally with water, 30–60 minutes before anticipated sexual activity. It can be taken with or without food, though heavy meals may delay dapoxetine’s effect. Never exceed 1 tablet per 24 hours. This is an as-needed medication, not a daily tablet.
Q3: How long does Extra Super Tadarise last?
Tadalafil’s erection-support effect can last up to 36 hours, earning it the nickname “the weekend pill.” Dapoxetine’s ejaculation-delaying effect peaks at about 1–1.2 hours and lasts approximately 1–3 hours.
Q4: Do I need a prescription?
Yes. Extra Super Tadarise is a prescription-only medicine (Rx). Titan Exim requires a valid prescription from a licensed physician for all orders. Self-medication is strongly discouraged given the serious contraindications and drug interactions involved.
Q5: Can I drink alcohol with Extra Super Tadarise?
Avoid alcohol. Combining alcohol with tadalafil and dapoxetine significantly increases the risk of orthostatic hypotension, dizziness, fainting, and other side effects. If you do consume alcohol, keep it to a minimum (no more than 1–2 units).
Q6: Can I take it with my blood pressure medication?
Use extreme caution. Tadalafil lowers blood pressure, and combining it with antihypertensives or alpha-blockers can cause a dangerous drop in BP. If you take any blood pressure medications, consult your doctor before using Extra Super Tadarise. Nitrate-based medications are absolutely contraindicated.
Q7: What if I’m already taking an antidepressant (SSRI)?
Do NOT take Extra Super Tadarise if you are currently on an SSRI (e.g., sertraline, fluoxetine, escitalopram), SNRI, or MAOI. Dapoxetine is itself a short-acting SSRI, and combining it with another serotonergic drug can cause serotonin syndrome, a potentially life-threatening condition. Inform your prescriber of all medications you take.
Q8: What are the most common side effects?
Common side effects include headache, facial flushing, indigestion, nasal congestion, back pain, dizziness, nausea, dry mouth, and fatigue. Most are mild and transient. Seek immediate medical care for any severe reaction such as prolonged erection (>4 hours), sudden vision or hearing changes, chest pain, or fainting.
Q9: Why buy from Titan Exim?
Titan Exim offer competitive pricing, discreet packaging, reliable global shipping, and dedicated customer support. All orders require valid prescription verification.
Why Choose Titan Exim Over Other Online Pharmacies?
| Feature | Typical Competitors | Titan Exim |
| Product Authenticity | Often unverified sourcing | 100% genuine, WHO-GMP certified manufacturer |
| Medical Content | Minimal (1–2 paragraphs) | Full clinical-grade product information |
| Pricing (90 tabs) | ~$115 | Competitive bulk pricing — contact for quote |
| Prescription Policy | Nominal verification | Strict Rx verification for patient safety |
| Shipping | Standard | Discreet global shipping with tracking |
| Customer Support | Email only | Dedicated sales & medical query support team |
― DISCLAIMER ―
The information on this page is intended for informational and educational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of a qualified healthcare provider before starting any new medication. Extra Super Tadarise is a prescription-only medication. Dapoxetine is not FDA-approved in the USA. Titan Exim does not encourage self-medication. All purchases are subject to valid prescription requirements, applicable local laws, and buyer responsibility.
――― SOURCES & REFERENCES ―――
All medical and clinical information on this page was compiled from authoritative, peer-reviewed, and government health sources:
[1] GoodRx – Tadalafil (Cialis): Uses, Side Effects, Alternatives & More – https://www.goodrx.com/cialis/what-is
[2] IndogenMed – Extra Super Tadarise Tablets | Tadalafil & Dapoxetine For ED/PE – https://indogenmed.org/product/extra-super-tadarise-tablets/
[3] NCBI StatPearls – PDE5 Inhibitors (Tadalafil mechanism of action) – https://www.ncbi.nlm.nih.gov/books/NBK549843/
[4] NICE Evidence Summary ESNM40 – Premature Ejaculation: Dapoxetine (Full Evidence Summary) – https://www.nice.org.uk/advice/esnm40/chapter/full-evidence-summary
[5] Wikipedia – Dapoxetine (Pharmacology, Side Effects, Mechanism) – https://en.wikipedia.org/wiki/Dapoxetine
[6] Sunrise Remedies Pvt. Ltd. – Extra Super Tadarise Product Information – https://sunriseremedies.in/our-products/extra-super-tadarise/
[7] NHS UK – About Tadalafil (Side Effects, Interactions, Storage) – https://www.nhs.uk/medicines/tadalafil/about-tadalafil/
[8] Baystate Health – Medication Storage Temperature Guidelines – https://www.baystatehealth.org/articles/medication-storage-temperature-guidelines




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